- Changes that can be percieved by people other than the patient or the practitioner. These can vary depending on the patient. People that know the individual well and can tell the patient has transformed and is no longer in a state of health. Such as family members, friends, or co-workers.

- Symptoms that the patient themselves feel, either aggravations or ammeliorations. This includes all the complaints that a patient has noticed such as lack of energy, sympathetic, depressed, etc. They can also get very specific such as times of days when it is better or worse and to what extent.

- Past incidents or accidents, known as occurents, such as childhood traumas, any possible negative drug reactions (vaccines, toxins, etc. ) Or anything that may have affected the patient and may have thrown the life force out of balance.

- The signs of disease noticed by the physician. The physician must use their supersensible forces to detect a possible underlying issue (tonic disease) and to detect the unsaid or any complaints that can’t be expressed by the patient only discerned by a supersensible thought based on a true dynamic view of disease. They must also help eliminate acute, self limiting diseases and relieve the uncomfortable flare ups to improve the quality of life of the patient.