The possible diseases in terms of how the disease trigger alters the healthy state. This aids in recognizing what needs to be cured and the specific path that needs to be taken.

They must know the curative properties of each particular medicine. The only two ways of obtaining this are clinical trials and provings.

They must link the medicine to the specific disease. Not only the matching of medicine to disease but the medicine has to be prepared properly with the right strength given in the right dose repetition.