Other Ingredients: Maltodextrin and magnesium stearate. Capsule consists of gelatin. Contains NO common allergen. NOTE: Color of product naturally varies from white to tan.

Keep in refrigerator.

The human gastrointestinal (GI) tract contains a large and diverse population of microorganisms – over 400 different bacterial species, most of which thrive in non- or low- oxygen environments. These flora increase in numbers and complexity along the length of the GI tract: the further down, the greater the number. The composition of the intestinal microflora also varies from one individual to another depending on diet, age, medication (antibiotics), stress levels, and physiological conditions.

Some species or strains of friendly flora “implant” (adhere to the intestinal and vaginal mucosa), while others are transient, reproducting while moving through the large intestines but not colonizing, and soon passing out in the stool. When probiotics implant, they “crowd out” competing pathogenic bacteria, taking away a vital “niche” in the intestinal ecology.

When the natural balance of the GI is disrupted, consuming probiotic bacteria via fermented foods or dietary supplements is essential to encouraging intestinal health. The term “probiotic” refers to a live microbial that beneficially affects the host by improving its microbial balance. In other words, the probiotics in JarroDophilus provide their health benefits by positively affecting the host’s intestinal tract.

Probiotic bacteria also product substances called bacteriocins, which they use to fight off competing, pathogenic species. Lactobacillus plantarum, for instance, produces the crucial plantaricin bacteriocin. As well, the peptidoglycans present in the cell walls of  Lactobacillus plantarum bacteria have been shown to be the reason for many of these organisms’ immune-supporting benefits, stimulating the production of cytokines (immune messengers) such as gamma interferon and interleukin 12 (IL-12), which are crucial for the TH1 immune response, while stimulating macrophage activity and Natural Killer cell function. Animal studies also demonstrate the direct ability of these cell wall components to kill cancer cells.

JarroDophilus utilizes synergistic groups of species that benefit each other. Mixed strain formulas are more economical, convenient, and effective than single species products. Research has found that supplying multiple groups of lactic acid bacteria together facilitates their replication. The important issues are 1) that the probiotic bacteria are available to the entire GI tract, and 2) that the strains be selected from the dominant Lactobacilli and Bifidobacteria.

Lactobacillus rhamnosus RO11 (sometimes mistakenly called Lactobacillus bifidus) has greater survivability than Lactobacillusacidophilus. This strain was discovered and developed by the Institute of Immunobiology and Virology in Belgrade. It produces prodigious amounts of polysaccharides, which aid adherence and stimulate immunity.

Lactobacillus plantarum is a remarkable species. It survives aerobic (air) and anaerobic (without air) conditions. It ferments 25 carbohydrates, survives high salt (10% solution), stomach pH or bile acids better thatn any other Lactobacillus species, and is capable of producing antioxidant activity! Lactobacillus plantarum ferments grains, grasses and vegetables and is a normal part of the diet.

Lactobacillus casei is often used to make fermented milk products and cheeses. It is popular in Japan and has been the subject of research including minor immunological effects in the GI tract involving the inhibition of pathogens.

Lactobacillus acidophilus R052 – This proprietary culture of Institut Rosell is of human origin and was selected by Dr. Brochu because of its ability to ferment 15 carbohydrates into lactic acid rather than the 11 carbohydrates typical of this species. Being a hardier strain, Lactobacillus acidophilus R052 displays superior production and survival.

Bifidobacterium breve is probably the most common bifidobacteria in infants, but it remains a lifelong resident throughout our lives. Bifidobacterium breve produces lactic acid, ferments over 20 carbohydrates and shares other characteristics in common with Bifidobacterium adolescentis.

Bifidobacterium longum BB536 (Morinaga strain) has been highly documented, with more than 30 years of research behind it. This strain from Japan implants, promoted bowel regularity, and antagonizes pathogens.

Combining JarroDophilus with Inulin-FOS

Inulin-FOS is a pure natural extract of chicory. It provides many health benefits similar to soluble dietary fiber. Being a non-digestible carbohydrate, it is not broken down by the digestive tract and therefore does not raise blood glucose levels in the body. No fermentation of sugar is used during the extraction of Inulin-FOS, as it is a plant extract. Inulin-FOS is used by the beneficial bacteria residing in the colon as a food source, promoting the growth of beneficial bacteria, which suppress harmful organisms.

JarroDophilus + Inulin-FOS is formulated with Institut Rosell’s own taxonomically defined strains from its culture collection developed over the past sixty years. The Institute is one of the most experienced producers of lactic acid-producing bacteria for food fermentation and probiotic supplementation in the world. They analyze and certify the type and potency of each organism contained in JarroDophilus + Inulin-FOS before release. 12-15 billion per gram is GUARANTEED. JarroDophilus + Inulin-FOS is the finest symbiotic combination probiotic/prebiotic product available.

Why Refrigeration is Required

Probiotics die off at warm temperatures. Loss is 10-15% per month at 70°F and more rapid at higher temperatures. However, non-refrigeration for as much as a week will not produce significant loss: in fact, even after a full year left out at room temperature, 75% of the probiotic bacteria should be viable. None the less, the product should be kept refrigerated. For a shelf-stable solution, see JarroDophilus EPS.

References

Chow JM. Probiotics and prebiotics: a brief overview. J Renal Nutr. 2002 Apr;12(2):76-86

Isolauri E. Probiotics in human disease. Am J Clin Nutr. 2001 Jun;73(6):1142S-1146S.

Elmer GW, Surawicz CM, McFarland LV. Biotherapeutic agents. A neglected modality for the treatment and prevention of selected intestinal and vaginal infections. JAMA. 1996 Mar 20;275(11):870-6.

Molin G. Probiotics in foods not containing milk or milk constituents, with special reference to Lactobacillus plantarum. Am J Clin Nutr. 2001 Feb;73(2 Suppl):380S-385S.

Mitsuoka T, Hidaka H, Eida T. Effect of fructo-oligosaccharides on intestinal microflora. Nahrung. 1987;31(5-6);427-36.

Isolauri E, Sutas Y, Kankaanpaa P, Arvilommi H, Salminen S. Probiotics: effects on immunity. Am J Clin Nutr. 2001 Feb;73(2 Suppl):444S-450S.